Endocrine Abstracts

Type 1B pseudohypoparathyroidism is characterised by renal resistance to parathyroid hormone in the absence of other endocrine or physical abnormalities. We present a 36-year-old lady with pseudohypoparathyroidism diagnosed aged seven following seizures with hypocalcaemia, hyperphosphataemia, elevated alkaline phosphatase, elevated parathyroid hormone (PTH) at 700 pg/mL (<120) and no cyclic AMP response to bovine PTH. There was no family history or diagnostic phenotypic fe...

We present the case of a 77-year-old lady who had a previous total pharyngo-laryngo-oesophagectomy for laryngeal squamous cell carcinoma. Her serum calcium had been normal on alfacalcidol and calcium supplementation for six months. She was admitted with dehydration and symptoms of hypercalcaemia on two different occasions, with corrected calcium 3.86 and 4.67 mmol/l. Each time she was treated with intravenous fluids and intravenous disodium pamidronate 60 mg by the admitting t...

A 64-year-old morbidly obese female was admitted with a history of bilateral lower leg ulceration, chronic venous insufficiency and biventricular cardiac failure. There was no relevant family history. She was commenced on furosemide and prophylactic enoxaparin. Biochemical investigations showed persistently elevated serum potassium concentrations (5.7 to 8.2 mmol/L) and low sodium levels (111 to 131 mmol/L). She had not been prescribed non-steroidal anti-inflammatory agents, a...